Risk factors for congenital heart diseases in Alexandria, Egypt.

作者: A. Bassili , S.A. Mokhtar , N.I. Dabous , S.R. Zaher , M.M. Mokhtar

DOI: 10.1023/A:1007601919164

关键词:

摘要: A matched case control study has been conducted in the children's hospitals Alexandria, Egypt, during 2 years-period, aiming at investigating risk factors for occurrence of congenital heart diseases. Our results showed that significant developing any type disease and ventricular septal defects were: older paternal age birth, positive consanguinity, family history, female sex hormones, irradiation, hazardous maternal occupation, diabetes mellitus suburban or rural residence. However, some environmental/teratogenic were not implicated etiology atrial pulmonary stenosis. These findings strongly suggest environmental vary according to specific disease. This emphasizes on need instruct public about importance pre-marital counseling deleterious effects various teratogens environment.

参考文章(36)
C J Biddle, F C Fraser, Estimating the risks for offspring of first-cousin matings. An approach. American Journal of Human Genetics. ,vol. 28, pp. 522- 526 ,(1976)
J. D. Erickson, M. M. Zack, Zhi-Hao Lian, Paternal age and the occurrence of birth defects. American Journal of Human Genetics. ,vol. 39, pp. 648- 660 ,(1986)
J M. Bland, D. G Altman, Multiple significance tests: the Bonferroni method BMJ. ,vol. 310, pp. 170- 170 ,(1995) , 10.1136/BMJ.310.6973.170
Samuel Shapiro, Olli P. Heinonen, Dennis Slone, Birth defects and drugs in pregnancy ,(1977)
RALPH G. GRABITZ, MICHEL R. JOFFRES, RUTH L. COLLINS-NAKAI, CONGENITAL HEART DISEASE: INCIDENCE IN THE FIRST YEAR OF LIFE THE ALBERTA HERITAGE PEDIATRIC CARDIOLOGY PROGRAM American Journal of Epidemiology. ,vol. 128, pp. 381- 388 ,(1988) , 10.1093/OXFORDJOURNALS.AJE.A114978
KENNETH J. ROTHMAN, DONALD C. FYLER, SEX, BIRTH ORDER, AND MATERNAL AGE CHARACTERISTICS OF INFANTS WITH CONGENITAL HEART DEFECTS American Journal of Epidemiology. ,vol. 104, pp. 527- 534 ,(1976) , 10.1093/OXFORDJOURNALS.AJE.A112326
Andrew F. Olshan, Patricia G. Schnitzer, Patricia A. Baird, Paternal age and the risk of congenital heart defects Teratology. ,vol. 50, pp. 80- 84 ,(1994) , 10.1002/TERA.1420500111
J S Tay, W C Yip, R Joseph, Parental age and birth order in Chinese children with congenital heart disease. Journal of Medical Genetics. ,vol. 19, pp. 441- 443 ,(1982) , 10.1136/JMG.19.6.441
C. Stoll, Y. Alembik, M. P. Roth, B. Dott, B. De Geeter, Risk factors in congenital heart disease. European Journal of Epidemiology. ,vol. 5, pp. 382- 391 ,(1989) , 10.1007/BF00144842