OSMOTICALLY INDUCED DRINKING IN THE GOAT: AN OSMORECEPTOR OR A SODIUM RECEPTOR MECHANISM?

摘要: Changes in sodium concentration and osmolality lateral ventricle cerebrospinal fluid (c.s.f.) caused by intracarotid infusion of hypertonic solutions were measured conscious goats. Intracarotid (1·5 ml.min−1) 1·0 or 2·0 mol.kg−1 urea 4·0 produced significant increases the c.s.f. 5 10 min after beginning infusion. No effect was seen following 0·15 M-NaCl. Only NaCl drinking. Blood significantly increased two as well urea. In conclusion, drinking goats peripheral administration is probably due to an osmoreceptor mechanism. A receptor mechanism unlikely because both but only osmotically effective solution