A Patient With BRAF V600E Lung Adenocarcinoma Responding to Vemurafenib

M. G. Kris, B. E. Johnson, D. J. Kwiatkowski, A. J. Iafrate, I. I. Wistuba, S. L. Aronson, J. A. Engelman, Y. Shyr, F. R. Khuri, C. M. Rudin, E. B. Garon, W. Pao, J. H. Schiller, E. B. Haura, K. Shirai, G. Giaccone, L. D. Berry, K. Kugler, J. D. Minna, P. A. Bunn, Identification of driver mutations in tumor specimens from 1,000 patients with lung adenocarcinoma: The NCI's Lung Cancer Mutation Consortium (LCMC). Journal of Clinical Oncology. ,vol. 29, ,(2011) , 10.1200/JCO.2011.29.15_SUPPL.CRA7506

Antonio Marchetti, Lara Felicioni, Sara Malatesta, Maria Grazia Sciarrotta, Luigi Guetti, Antonio Chella, Patrizia Viola, Carmela Pullara, Felice Mucilli, Fiamma Buttitta, Clinical Features and Outcome of Patients With Non–Small-Cell Lung Cancer Harboring BRAF Mutations Journal of Clinical Oncology. ,vol. 29, pp. 3574- 3579 ,(2011) , 10.1200/JCO.2011.35.9638

Christine A. Pratilas, Aphrothiti J. Hanrahan, Ensar Halilovic, Yogindra Persaud, Junichi Soh, Dhananjay Chitale, Hisayuki Shigematsu, Hiromasa Yamamoto, Ayana Sawai, Manickam Janakiraman, Barry S. Taylor, William Pao, Shinichi Toyooka, Marc Ladanyi, Adi Gazdar, Neal Rosen, David B. Solit, Genetic predictors of MEK-dependence in non-small cell lung cancer Cancer Research. ,vol. 68, pp. 9375- 9383 ,(2008) , 10.1158/0008-5472.CAN-08-2223

Paolo Ascierto, James Larkin, Reinhard Dummer, Claus Garbe, Alessandro Testori, Michele Maio, David Hogg, Paul Lorigan, Celeste Lebbe, Thomas Jouary, Dirk Schadendorf, Antoni Ribas, Steven J. O'Day, Jeffrey A. Sosman, John M. Kirkwood, Alexander M.M. Eggermont, Brigitte Dreno, Keith Nolop, Jiang Li, Betty Nelson, Jeannie Hou, Richard J. Lee, Keith T. Flaherty, Grant A. McArthur, Paul B. Chapman, Axel Hauschild, Caroline Robert, John B. Haanen, Improved Survival with Vemurafenib in Melanoma with BRAF V600E Mutation The New England Journal of Medicine. ,vol. 364, pp. 2507- 2516 ,(2011) , 10.1056/NEJMOA1103782

Jeffrey A. Sosman, Kevin B. Kim, Lynn Schuchter, Rene Gonzalez, Anna C. Pavlick, Jeffrey S. Weber, Grant A. McArthur, Thomas E. Hutson, Stergios J. Moschos, Keith T. Flaherty, Peter Hersey, Richard Kefford, Donald Lawrence, Igor Puzanov, Karl D. Lewis, Ravi K. Amaravadi, Bartosz Chmielowski, H. Jeffrey Lawrence, Yu Shyr, Fei Ye, Jiang Li, Keith B. Nolop, Richard J. Lee, Andrew K. Joe, Antoni Ribas, Survival in BRAF V600–Mutant Advanced Melanoma Treated with Vemurafenib The New England Journal of Medicine. ,vol. 366, pp. 707- 714 ,(2012) , 10.1056/NEJMOA1112302