Mammalian cardiolipin biosynthesis.
作者： Edgard M. Mejia , Hieu Nguyen , Grant M. Hatch
DOI: 10.1016/J.CHEMPHYSLIP.2013.10.001
关键词:
摘要: Cardiolipin is a major phospholipid in mitochondria and involved the generation of cellular energy form ATP. In mammalian eukaryotic cells it synthesized via cytidine-5'-diphosphate-1,2-diacyl-sn-glycerol phosphate pathway. This brief review will describe some more recent studies on cardiolipin biosynthesis provide an overview regulation biosynthesis. addition, important role that this key plays disease processes including heart failure, diabetes, thyroid hormone genetic Barth Syndrome be discussed.
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