Altered Neural Cell Fates and Medulloblastoma in MousepatchedMutants

作者: Lisa V. Goodrich , Ljiljana Milenković , Kay M. Higgins , Matthew P. Scott

DOI: 10.1126/SCIENCE.277.5329.1109

关键词:

摘要: The PATCHED (PTC) gene encodes a Sonic hedgehog (Shh) receptor and a tumor suppressor protein that is defective in basal cell nevus syndrome (BCNS). Functions ofPTC were …

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