Efficient separation of biological macromolecular proteins by polyethersulfone hollow fiber ultrafiltration membranes modified with Fe3O4 nanoparticles-decorated carboxylated graphene oxide nanosheets.
作者： Akshay Modi , Jayesh Bellare
DOI: 10.1016/J.IJBIOMAC.2019.05.200
关键词:
摘要: Abstract The separation of biological macromolecules, e.g., proteins, using ultrafiltration membranes in the biotechnology, food and pharmaceutical industries has gained significant attention research community. In this work, iron oxide nanoparticles-decorated carboxylated graphene nanosheets (Fe3O4/cGO nanohybrid) were synthesized incorporated polyethersulfone (PES) hollow fiber (HFMs) resulting modified evaluated for namely lysozyme, trypsin, pepsin, human serum albumin, γ-globulin fibrinogen. physicochemical properties, mainly mechanical strength, hydrophilicity, porosity, pore size, surface roughness found to be favorable HFMs. These properties helped composite (HFMs with 0.1 wt% Fe3O4/cGO achieving remarkably high pure water flux (110.0 ± 3.8 L/m2 h) as 97.8% recovery. PES-Fe3O4/cGO HFMs showed significantly rejection lysozyme (92.9 ± 1.3%), trypsin (94.5 ± 1.1%), pepsin (96.9 ± 1.2%), albumin (99.5 ± 0.5%), (100%), fibrinogen (100%). also maintained their efficacious performance during long-term studies. Therefore, nanohybrid are potential efficient biomolecules, particularly proteins industries.
sci-hub.se 参考文章(51)
Advanced membrane technology and applications J. Wiley. ,(2008) , 10.1002/9780470276280
Raja Ghosh, None, Application of Membranes in Biotechnology Encyclopedia of Membrane Science and Technology. pp. 1- 19 ,(2013) , 10.1002/9781118522318.EMST125
R. Mahendran, R. Malaisamy, G. Arthanareeswaran, D. Mohan, Cellulose acetate–poly(ether sulfone) blend ultrafiltration membranes. II. Application studies Journal of Applied Polymer Science. ,vol. 92, pp. 3659- 3665 ,(2004) , 10.1002/APP.20302
Indok Nurul Hasyimah Mohd Amin, Abdul Wahab Mohammad, Nidal Hilal, None, Description of membrane fouling characteristics during ultrafiltration of organic foulants contained in sweetwater solutions Journal of environmental chemical engineering. ,vol. 2, pp. 1243- 1251 ,(2014) , 10.1016/J.JECE.2014.05.015
R Ghosh, Z.F Cui, Protein purification by ultrafiltration with pre-treated membrane Journal of Membrane Science. ,vol. 167, pp. 47- 53 ,(2000) , 10.1016/S0376-7388(99)00275-6
Law Yong Ng, Abdul Wahab Mohammad, Choe Peng Leo, Nidal Hilal, None, Polymeric membranes incorporated with metal/metal oxide nanoparticles: A comprehensive review Desalination. ,vol. 308, pp. 15- 33 ,(2013) , 10.1016/J.DESAL.2010.11.033
Meng Hu, Baoxia Mi, Enabling graphene oxide nanosheets as water separation membranes. Environmental Science & Technology. ,vol. 47, pp. 3715- 3723 ,(2013) , 10.1021/ES400571G
MaryTheresa M. Pendergast, Eric M.V. Hoek, A review of water treatment membrane nanotechnologies Energy and Environmental Science. ,vol. 4, pp. 1946- 1971 ,(2011) , 10.1039/C0EE00541J
Akon Higuchi, Satoko Mishima, Tsutomu Nakagawa, Separation of proteins by surface modified polysulfone membranes Journal of Membrane Science. ,vol. 57, pp. 175- 185 ,(1991) , 10.1016/S0376-7388(00)80677-8
P. Kanagaraj, A. Nagendran, D. Rana, T. Matsuura, S. Neelakandan, Separation of macromolecular proteins and rejection of toxic heavy metal ions by PEI/cSMM blend UF membranes International Journal of Biological Macromolecules. ,vol. 72, pp. 223- 229 ,(2015) , 10.1016/J.IJBIOMAC.2014.08.018