Synthesis, characterization, and anticancer properties of iminophosphineplatinum(II) complexes containing boronate esters
作者： Patrick-Denis St-Coeur , Samantha Kinley , Christopher M. Vogels , Andreas Decken , Pier Jr. Morin
关键词:
摘要: Three new iminophosphines containing pinacol-derived boronate esters have been prepared and ligated to dichloridoplatinum(II) fragments. All compounds characterized fully, including an X-ray diffraction study carried out for the platinum complex 8, which is derived from 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline. These three complexes, along with non-boron control, examined their initial cytotoxic properties against two glioma cell lines using MTT method.
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