Syntheses and anti-tubercular activity of β-substituted and α,β-disubstituted peptidyl β-aminoboronates and boronic acids.
作者： Alexey S Gorovoy , Olga Gozhina , John‐Sigurd Svendsen , George V Tetz , Anna Domorad
DOI: 10.1002/PSC.2537
关键词: In vitro 、 Tuberculosis 、 Stereochemistry 、 Anti tubercular 、 Peptide 、 Chemistry 、 Mycobacterium tuberculosis 、 Antibacterial peptide 、 Biochemistry
摘要: Tuberculosis is still affecting millions of people worldwide, and new resistant strains Mycobacterium tuberculosis are being found. It therefore necessary to find compounds for treatment. In this paper, we report the synthesis in vitro testing peptidyl β-aminoboronic acids β-aminoboronates with anti-tubercular activity. Copyright © 2013 European Peptide Society John Wiley & Sons, Ltd.
sci-hub.se 参考文章(18)
H. Herzog, Basel, History of Tuberculosis Respiration. ,vol. 65, pp. 5- 15 ,(1998) , 10.1159/000029220
Hugo L. David, Probability Distribution of Drug-Resistant Mutants in Unselected Populations of Mycobacterium tuberculosis Applied Microbiology. ,vol. 20, pp. 810- 814 ,(1970) , 10.1128/AM.20.5.810-814.1970
Bengt Erik Haug, John S Svendsen, The role of tryptophan in the antibacterial activity of a 15-residue bovine lactoferricin peptide. Journal of Peptide Science. ,vol. 7, pp. 190- 196 ,(2001) , 10.1002/PSC.318
Rajendra Prasad Singh, Donald S. Matteson, Asymmetric Homologation of Boronic Esters Bearing Azido and Silyloxy Substituents Journal of Organic Chemistry. ,vol. 65, pp. 6650- 6653 ,(2000) , 10.1021/JO005522B
Helen D Donoghue, Mark Spigelman, Charles L Greenblatt, Galit Lev-Maor, Gila Kahila Bar-Gal, Carney Matheson, Kim Vernon, Andreas G Nerlich, Albert R Zink, Tuberculosis: from prehistory to Robert Koch, as revealed by ancient DNA. Lancet Infectious Diseases. ,vol. 4, pp. 584- 592 ,(2004) , 10.1016/S1473-3099(04)01133-8
J. M. Grange, Effective vaccination against tuberculosis-a new ray of hope. Clinical and Experimental Immunology. ,vol. 120, pp. 232- 234 ,(2000) , 10.1046/J.1365-2249.2000.01145.X
Mohammad Asif, Anees A. Siddiqui, Asif Husain, Quinolone derivatives as antitubercular drugs Medicinal Chemistry Research. ,vol. 22, pp. 1029- 1042 ,(2013) , 10.1007/S00044-012-0101-3
Donald S. Matteson, Ellen C. Beedle, Erik Christenson, Michael A. Dewey, Mark L. Peterson, A chiral synthesis of (2S, 3S)‐phenylalanine‐3‐2H via boronic esters Journal of Labelled Compounds and Radiopharmaceuticals. ,vol. 25, pp. 675- 683 ,(1988) , 10.1002/JLCR.2580250613
Morten B Strøm, Bengt Erik Haug, Øystein Rekdal, Merete L Skar, Wenche Stensen, John S Svendsen, Important structural features of 15-residue lactoferricin derivatives and methods for improvement of antimicrobial activity Biochemistry and Cell Biology. ,vol. 80, pp. 65- 74 ,(2002) , 10.1139/O01-236
Donald S. Matteson, Ellen C. Beedle, A directed chiral synthesis of amino acids from boronic esters Tetrahedron Letters. ,vol. 28, pp. 4499- 4502 ,(1987) , 10.1016/S0040-4039(00)96547-X