Structural basis for recognition of hemi-methylated DNA by the SRA domain of human UHRF1
作者： George V. Avvakumov , John R. Walker , Sheng Xue , Yanjun Li , Shili Duan
DOI: 10.1038/NATURE07273
关键词:
摘要: … Given the known ability of UHRF1 to bind to DNMT1, our findings support the hypothesis that UHRF1 is a factor involved in increasing the efficacy of DNMT1 methylation of hemi-…
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R Holliday, J. Pugh, How Are Alkynes Scrambled Science. ,vol. 308, pp. 216- 217 ,(2005) , 10.1126/SCIENCE.1111098
Thomas C. Terwilliger, Joel Berendzen, Automated MAD and MIR structure solution Acta Crystallographica Section D-biological Crystallography. ,vol. 55, pp. 849- 861 ,(1999) , 10.1107/S0907444999000839
Lianna M. Johnson, Magnolia Bostick, Xiaoyu Zhang, Edward Kraft, Ian Henderson, Judy Callis, Steven E. Jacobsen, The SRA Methyl-Cytosine-Binding Domain Links DNA and Histone Methylation Current Biology. ,vol. 17, pp. 379- 384 ,(2007) , 10.1016/J.CUB.2007.01.009
Xiaodong Cheng, Robert M. Blumenthal, Mammalian DNA Methyltransferases: A Structural Perspective Structure. ,vol. 16, pp. 341- 350 ,(2008) , 10.1016/J.STR.2008.01.004
Steen K.T. Ooi, Timothy H. Bestor, Cytosine Methylation: Remaining Faithful Current Biology. ,vol. 18, ,(2008) , 10.1016/J.CUB.2007.12.045
Motoko Unoki, Toshihiko Nishidate, Yusuke Nakamura, ICBP90, an E2F-1 target, recruits HDAC1 and binds to methyl-CpG through its SRA domain. Oncogene. ,vol. 23, pp. 7601- 7610 ,(2004) , 10.1038/SJ.ONC.1208053
Motoko Unoki, Christian Bronner, Marc Mousli, A Concern Regarding the Current Confusion with the Human Homolog of Mouse Np95, ICBP90/UHRF1 Radiation Research. ,vol. 169, pp. 240- 244 ,(2008) , 10.1667/RR1209.1
Charmaine Hoang, Adrian R. Ferré-D'Amaré, Cocrystal structure of a tRNA Psi55 pseudouridine synthase: nucleotide flipping by an RNA-modifying enzyme. Cell. ,vol. 107, pp. 929- 939 ,(2001) , 10.1016/S0092-8674(01)00618-3
G. N. Murshudov, A. A. Vagin, E. J. Dodson, Refinement of macromolecular structures by the maximum-likelihood method. Acta Crystallographica Section D-biological Crystallography. ,vol. 53, pp. 240- 255 ,(1997) , 10.1107/S0907444996012255
Jeffrey A. Yoder, Neilesh S. Soman, Gregory L. Verdine, Timothy H. Bestor, DNA (cytosine-5)-methyltransferases in mouse cells and tissues. Studies with a mechanism-based probe Journal of Molecular Biology. ,vol. 270, pp. 385- 395 ,(1997) , 10.1006/JMBI.1997.1125