EPIDERMAL-GROWTH-FACTOR RECEPTOR STATUS AS PREDICTOR OF EARLY RECURRENCE OF AND DEATH FROM BREAST CANCER
作者： J. Richard , C. Sainsbury , GeoffreyK. Needham , JohnR. Farndon , ArchieJ. Malcolm
DOI: 10.1016/S0140-6736(87)90593-9
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摘要: In 135 primary breast cancers, there was a significant inverse relation between epidermal-growth-factor receptor (EGFR) and oestrogen (ER) status, association with tumour size poor differentiation. The relapse-free survival overall were significantly worse for patients EGFR+ tumours compared EGFR- tumours. Relapse-free also ER- ER+ Of the 71 28 43 EGFR-. but than "double-negative" patients. Moreover, similar to those Thus EGFR status divides population into good prognosis subgroups. presence of most important variable in predicting survival. Multivariate analysis showed that lymph-node-negative patients, second lymph-node positive
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