作者: Jaime E Ordóñez , John J Orozco
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摘要: Background: Nowadays, there are two vaccination strategies in Colombia to prevent pneumococcal diseases people over 50 years. Our aim is estimate cost-effectiveness of conjugate vaccine 13-valent (PCV13) versus polysaccharide 23-valent (PPSV23) and their related mortality years old Colombia. Methods: A Markov model was developed with national data, including serotypes distribution between 2005 2010. Vaccination a cohort simulated five year time horizon assumed. Analysis done from perspective third party payer. Direct costs were provided by insurance company; sensitive univariate probabilistic analysis for epidemiological clinical effectiveness parameters costs.