作者: Jun Sugawara , Koichiro Hayashi , Takashi Yokoi , Hirofumi Tanaka
DOI: 10.1016/J.JCMG.2008.06.010
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摘要: Objectives To determine whether human aorta lengthens with aging and to evaluate the impact of hypothesized aortic elongation on pulse wave velocity (PWV) measurements. Background Although it is generally thought that becomes tortuous aging, there has been no systematic study date in healthy adults if this so. Such age-related may be a confounding factor for PWV measurement elderly people. Methods Arterial lengths were computed by 3-dimensional transverse magnetic resonance image arterial tracing carotid iliac arteries 256 apparently (age 19 79 years). Results The ascending was greater advancing age (r = 0.72), whereas descending not associated age. corresponding increases (beta 0.50) brachial/aortic pressure ratio 0.24), which an index amplification. straight distance between femoral sites (car-fem), most popular length measurement, overestimated measured ∼25%. accurate estimation obtained subtracting from car-fem, Conclusions age, even humans, due primarily aorta. Age-related little measurements, as aorta, undergoes lengthening included