Oxidative stress and neuroinflammation in Alzheimer's disease and amyotrophic lateral sclerosis: common links and potential therapeutic targets
作者： Molina Mhatre , Robert A. Floyd , Kenneth Hensley
关键词:
摘要: … ALS, and a body of Alzheimer’s disease findings, we hypothesize a prominent pathological role for the TNFα-signaling axis and neuroinflammation in the pathogenesis of both diseases…
medra.org 参考文章(109)
P.L. McGeer, H. Akiyama, S. Itagaki, E.G. McGeer, Immune system response in Alzheimer's disease. Canadian Journal of Neurological Sciences. ,vol. 16, pp. 516- 527 ,(1989) , 10.1017/S0317167100029863
P F Good, A Hsu, D P Perl, P Werner, C W Olanow, Evidence of neuronal oxidative damage in Alzheimer's disease. American Journal of Pathology. ,vol. 149, pp. 21- 28 ,(1996)
Rogers J, Bonnell B, Webster S, Charge-based binding of complement component C1q to the Alzheimer amyloid beta-peptide. American Journal of Pathology. ,vol. 150, pp. 1531- 1536 ,(1997)
Elisabeth Tarkowski, Kaj Blennow, Anders Wallin, Andrzej Tarkowski, Intracerebral production of tumor necrosis factor-alpha, a local neuroprotective agent, in Alzheimer disease and vascular dementia. Journal of Clinical Immunology. ,vol. 19, pp. 223- 230 ,(1999) , 10.1023/A:1020568013953
Tolga Uz, Christine Pesold, Patrizia Longone, Hari Manev, Aging-associated up-regulation of neuronal 5-lipoxygenase expression: putative role in neuronal vulnerability The FASEB Journal. ,vol. 12, pp. 439- 449 ,(1998) , 10.1096/FASEBJ.12.6.439
Liya Qin, Yuxin Liu, Cynthia Cooper, Bin Liu, Belinda Wilson, Jau-Shyong Hong, Microglia enhance β‐amyloid peptide‐induced toxicity in cortical and mesencephalic neurons by producing reactive oxygen species Journal of Neurochemistry. ,vol. 83, pp. 973- 983 ,(2002) , 10.1046/J.1471-4159.2002.01210.X
Corrada Bonaiuto, Marco A. Cassatella, Alberto Mantovani, Laszlo Otvos, Filippo Rossi, Lucia Meda, Silvano Sozzani, Dan Zhou, Sergio Bernasconi, Beta-amyloid (25-35) peptide and IFN-gamma synergistically induce the production of the chemotactic cytokine MCP-1/JE in monocytes and microglial cells. Journal of Immunology. ,vol. 157, pp. 1213- 1218 ,(1996)
Robert M. Friedlander, Robert H. Brown, Valeria Gagliardini, Joy Wang, Junying Yuan, Inhibition of ICE slows ALS in mice Nature. ,vol. 388, pp. 31- 31 ,(1997) , 10.1038/40299
C. W. Cotman, C. G. Glabe, A. J. Tenner, D. Burdick, Haixiang Jiang, beta-Amyloid activates complement by binding to a specific region of the collagen-like domain of the C1q A chain Journal of Immunology. ,vol. 152, pp. 5050- 5059 ,(1994)
Chengyu Jiang, Adrian T. Ting, Brian Seed, PPAR-γ agonists inhibit production of monocyte inflammatory cytokines Nature. ,vol. 391, pp. 82- 86 ,(1998) , 10.1038/34184