Hemodynamic analysis of esophageal varices in patients with liver cirrhosis using color Doppler ultrasound

摘要: AIM: To study the portal hemodynamics and their relationship with size of esophageal varices seen at endoscopy to evaluate whether these Doppler ultrasound parameters might predict variceal bleeding in patients liver cirrhosis hypertension. METHODS: One hundred twenty cirrhotic but without any previous were enrolled prospective study. During a 2-year observation period, 52 who had least one episode acute hemorrhage constituted group, remaining 68 non-bleeding group. All underwent before or after color Doppler-ultrasonic examination, images interpreted independently by two endoscopists. The control group consisted 30 healthy subjects, matched patient age gender. Measurements diameter, flow direction velocity left gastric vein (LGV) (PV) done all controls using unit. After baseline measurements, min oral administration 75 g glucose 225 mL, changes PV LGV examined 60 15 controls. RESULTS: detected successfully 115 (96%) 105 (88%) 120 patients, respectively, 27 (90%) 21 (70%) controls, respectively. Among 37 F1, 59 F2, 24 F3 grade varices. Compared significantly lower PV, greater diameter LGV, higher LGV. In no difference observed between (EVB). However, blood for EVB (+) compared (-) (P 6 mm. was 8.70±1.91 cm/s (n = 21). cirrhosis, it 10.3±2.1 12) when hepatopetal 13.5±2.3 87) hepatofugal. As enlarged, hepatofugal increased (32 61.5%). Within mean 16.6±2.62 cm/s. No correlation EVB. hepatopetal, toward PV. F1 varices, 10 to-and-fro state 3 18. 91% F2 Changes not significant ingestion (PV: 1.41±1.5 cm 1.46±1.6 after; LGV: 0.57±1.7 0.60±1.5 after). Flow 16 44 glucose. changed 9 increase 38 (86%) There percentage Patients responded excessively food have high risk bleeding. than those (LGV: 28.3±26.1%, PV: 7.2±13.2%, P<0.01), whereas occurred subjects. CONCLUSION: Hemodynamics is unrelated degree endoscopic abnormalities cirrhosis. most important combinations are findings followed hemodynamics. Duplex-Doppler ultrasonography has value identification appears be superior predicting