Antitumor and Wound Healing Properties of Rubus niveus Thunb. Root

作者: Blassan Plackal George , Thangaraj Parimelazhagan , Thankarajan Sajeesh , Shanmugam Saravanan , None

DOI: 10.1615/JENVIRONPATHOLTOXICOLONCOL.2014010949

关键词:

摘要: The main objective of this study is to highlight the importance Rubus niveus in pharmaceu- tical industry for development cost-effective drugs. was undertaken explore HPLC profile, wound healing, antitumor, and free radical scavenging properties R. niveus. root extracted using organic solvents subjected vitro antioxidant assays. Acetone extract, which showed better properties, evaluated vivo antioxidant, antitumor properties. poly- phenolic acetone extract significant In healing study, complete epithelialization noticed during 13th 17th days treated groups. 250 mg/kg group found prolong life span mice with Ehrlich ascites carcinoma (70.04%) reduced volume Daltons lymphoma solid tumors (2.07 cm3). analysis revealed presence Quercetin, a natural flavonoid retention time 20.89 min. results current suggest use as valuable that has an immense scope effective source cure skin diseases, wounds, tumors.

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