Molecular cloning of odorant-binding protein: member of a ligand carrier family.
作者： J Pevsner , R. Reed , P. Feinstein , S. Snyder
关键词:
摘要: Odorant-binding protein (OBP) is found in nasal epithelium, and it selectively binds odorants. Three complementary DNAs encoding rat odorant-binding have now been cloned sequenced. One clone contains an open reading frame predicted to encode 18,091-dalton protein. RNA blot analysis confirms the localization of OBP messenger epithelium. This has 33 percent amino acid identity alpha 2-microglobulin, a secreted plasma Other members 2-microglobulin superfamily bind transport hydrophobic ligands. Thus, probably carries odorants within epithelium putative olfactory receptors.
sciencemag.org
harvard.edu
elsevier.com参考文章(30)
R. Lathe, Synthetic oligonucleotide probes deduced from amino acid sequence data. Theoretical and practical considerations. Journal of Molecular Biology. ,vol. 183, pp. 1- 12 ,(1985) , 10.1016/0022-2836(85)90276-1
G.A. Ricca, J.M. Taylor, Nucleotide sequence of rat alpha 1-acid glycoprotein messenger RNA. Journal of Biological Chemistry. ,vol. 256, pp. 11199- 11202 ,(1981) , 10.1016/S0021-9258(19)68577-7
S. Ottonello, S. Petrucco, G. Maraini, Vitamin A uptake from retinol-binding protein in a cell-free system from pigment epithelial cells of bovine retina. Retinol transfer from plasma retinol-binding protein to cytoplasmic retinol-binding protein with retinyl-ester formation as the intermediate step. Journal of Biological Chemistry. ,vol. 262, pp. 3975- 3981 ,(1987) , 10.1016/S0021-9258(18)61298-0
D E Brooks, A R Means, E J Wright, S P Singh, K K Tiver, Molecular cloning of the cDNA for two major androgen-dependent secretory proteins of 18.5 kilodaltons synthesized by the rat epididymis. Journal of Biological Chemistry. ,vol. 261, pp. 4956- 4961 ,(1986) , 10.1016/S0021-9258(19)89198-6
P B Sklar, R R Anholt, S H Snyder, The odorant-sensitive adenylate cyclase of olfactory receptor cells. Differential stimulation by distinct classes of odorants. Journal of Biological Chemistry. ,vol. 261, pp. 15538- 15543 ,(1986) , 10.1016/S0021-9258(18)66747-X
D Drayna, C Fielding, J McLean, B Baer, G Castro, E Chen, L Comstock, W Henzel, W Kohr, L Rhee, Cloning and expression of human apolipoprotein D cDNA. Journal of Biological Chemistry. ,vol. 261, pp. 16535- 16539 ,(1986) , 10.1016/S0021-9258(18)66599-8
Finn Bojsen-Møller, TOPOGRAPHY OF THE NASAL GLANDS IN RATS AND SOME OTHER MAMMALS. Anatomical Record-advances in Integrative Anatomy and Evolutionary Biology. ,vol. 150, pp. 11- 24 ,(1964) , 10.1002/AR.1091500103
D. Schubert, P. Berman, P. Gray, E. Chen, K. Keyser, D. Ehrlich, H. Karten, M. LaCorbiere, F. Esch, Sequence analysis, cellular localization, and expression of a neuroretina adhesion and cell survival molecule. Cell. ,vol. 51, pp. 135- 142 ,(1987) , 10.1016/0092-8674(87)90018-3
S Pervaiz, K Brew, Homology of beta-lactoglobulin, serum retinol-binding protein, and protein HC. Science. ,vol. 228, pp. 335- 337 ,(1985) , 10.1126/SCIENCE.2580349
S. C. BELL, J. W. KEYTE, Amino-acid sequence similarities. Nature. ,vol. 329, pp. 296- 296 ,(1987) , 10.1038/329296A0