Six-of-the-best: unique contributions of γδ T cells to immunology

摘要: γδ T cells are a unique and conserved population of lymphocytes that have been the subject recent explosion interest owing to their essential contributions many types immune response immunopathology. But what does integration long-established studies really tell us about these place in immunology? The time is ripe consider evidence for crucial functions. We conclude whereas B αβ commonly thought contribute primarily antigen-specific effector memory phases immunity, distinct they combine conventional adaptive features (inherent cell receptors pleiotropic functions) with rapid, innate-like responses can them initiation phase reactions. This underpins revised perspective on lymphocyte biology regulation immunogenicity.