Correlation of 140S antigen dose with the serum neutralizing antibody response and the level of protection induced in cattle by foot-and-mouth disease vaccines.
作者： T.W.F. Pay , P.J. Hingley
DOI: 10.1016/0264-410X(87)90011-9
关键词:
摘要: An analysis was made of data from potency tests on fifteen batches monovalent foot-and-mouth disease vaccine, comprising five each type O, A and C. Regressions were calculated for the relation percentage protection (probit) versus log 140S antigen dose serum neutralizing antibody titre (log SN50) dose. Type O vaccines required a far higher level (220 ng) to achieve 50% (PA50) in cattle than did (2.4 C (4.36 vaccines. antigen, dose, as effective at provoking types antigens. Thus, it would appear that SN50 value (2.14) equate with (1.17) (1.41) Prior 1977, however, PA50 vaccine strain only 1.34 concluded an antigenic shift most likely cause large difference between current value.
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