Renal morphology in pigs with experimental hyperparathyroidism. Light-microscopic findings and some functional aspects.

作者: Lennart Boquist , Bengt Fåhraeus

DOI: 10.1111/J.1699-0463.1975.TB01365.X

关键词:

摘要: Ultrastructural examinations were performed in three groups of pigs: one sham-operated control group, group subjected to thyroidectomy, and another injected with parathormone after thyroidectomy (TX + PTH). Attention was mainly paid the localization structural details calcium deposits which found TX PTH 78 150 hours first injection. Calcium epithelial cells lumina tubular system, especially proximal convoluted tubules. It is suggested that deposited mitochondria cytoplasmic vacuoles larger calcific bodies, occasionally concentric lamellation, are formed by coalescence small particles, induce degenerative changes epithelium may lead discharge material into lumina.

参考文章(31)
Howard Levitin, Franklin H. Epstein, David Beck, Frank A. Carone, The Effects Upon the Kidney of Transient Hypercalcemia Induced by Parathyroid Extract American Journal of Pathology. ,vol. 36, pp. 77- 103 ,(1960)
J. B. Caulfield, P. E. Schrag, ELECTRON MICROSCOPIC STUDY OF RENAL CALCIFICATION. American Journal of Pathology. ,vol. 44, pp. 365- 381 ,(1964)
Ib Transbøl, Ib Homum, Steffen Hahnemann, Eivin Hasner, Henrik Øhlenschlaeger, Henrik Diemer, Knud Lockwood, Tubular reabsorption of calcium in the differential diagnosis of hypercalcaemia. Further experience. Acta Medica Scandinavica. ,vol. 188, pp. 505- 522 ,(2009) , 10.1111/J.0954-6820.1970.TB08076.X
G.A. Charbon, A rapid and selective vasodilator effect of parathyroid hormone European Journal of Pharmacology. ,vol. 3, pp. 275- 278 ,(1968) , 10.1016/0014-2999(68)90144-1
A. F. SCHNEIDER, E. P. HEAVEN, G. REAVEN, A comparison of renal calcification produced by parathyroid extract or calcium gluconate. Endocrinology. ,vol. 67, pp. 733- 743 ,(1960) , 10.1210/ENDO-67-6-733
Harold M. Price, James B. Hanrahan, Robert G. Florida, Morphogenesis of calcium laden cytoplasmic bodies in malakoplakia of the skin: An electron microscopic study Human Pathology. ,vol. 4, pp. 381- 394 ,(1973) , 10.1016/S0046-8177(73)80100-5
Franklin H. Epstein, Calcium and the kidney The American Journal of Medicine. ,vol. 45, pp. 700- 714 ,(1968) , 10.1016/0002-9343(68)90206-4
Lave Ohlsson, RENAL FUNCTION IN HYPERPARATHYROIDISM European Journal of Endocrinology. ,vol. 63, pp. 161- 174 ,(1970) , 10.1530/ACTA.0.0630161