Phytoestrogenic formulations for alleviation or prevention of menopausal symptoms

摘要: Select phytoestrogen pharmaceutical compositions and methods of use for preventing or reducing one more symptoms associated with pre menopause, and/or post menopause are described herein. These select formulations composed only two plant-derived estrogenic molecules their structural analogues exhibit binding preference to ERβ over ERα agonist activity in the brain. ERβ-selective cross blood-brain-barrier promote estrogen-associated neurotrophism neuroprotection mechanisms brain, without activating proliferative reproductive tissues therefore devoid other problematic aspects. The can be administered enterally, transdermally, transmucosally, intranasally parenterally. preferably contain combinations compounds, formulated daily, sustained, delayed weekly/monthly administration. In a preferred embodiment, these women who menopausal, most early menopausal.