Influence of pH on the build-up of poly-L-lysine/heparin multilayers.

作者: Alejandro Barrantes , Olga Santos , Javier Sotres , Thomas Arnebrant

DOI: 10.1016/J.JCIS.2012.08.008

关键词:

摘要: The effect of pH on the build-up polyelectrolyte multilayers, PEMs, composed by poly-L-lysine and heparin onto two different substrates, silica gold, has been studied means ellipsometry quartz crystal microbalance with dissipation, QCM-D. Ellipsometry results indicate that dry mass grows exponentially number layers, this amount is larger as values are raised. From QCM-D data viscoelastic properties multilayered structure have obtained. These reflect PEMs become more increased for while gold highest behavior obtained at neutral elastic becomes dominant further or decreased. By combining these surface techniques it also possible to determine solvent content in multilayers reach a deeper understanding internal structure.

参考文章(58)
Alejandro Barrantes, Maria T Rejas, Maria J Benitez, Juan S Jiménez, Interaction between Alzheimer's Aβ1-42 Peptide and DNA Detected by Surface Plasmon Resonance Journal of Alzheimer's Disease. ,vol. 12, pp. 345- 355 ,(2007) , 10.3233/JAD-2007-12408
Alejandro Barrantes, Javier Sotres, Mercedes Hernando-Perez, Maria J Benitez, Pedro J De Pablo, Arturo M Baro, Jesus Avila, Juan S Jimenez, Tau aggregation followed by atomic force microscopy and surface plasmon resonance, and single molecule tau-tau interaction probed by atomic force spectroscopy. Journal of Alzheimer's Disease. ,vol. 18, pp. 141- 151 ,(2009) , 10.3233/JAD-2009-1130
P.A. Cuypers, Dynamic ellipsometry, biochemical and biomedical applications Rijksuniversiteit Limburg. ,(1976)
Changsheng Shan, Huafeng Yang, Dongxue Han, Qixian Zhang, Ari Ivaska, Li Niu, Water-soluble graphene covalently functionalized by biocompatible poly-L-lysine Langmuir. ,vol. 25, pp. 12030- 12033 ,(2009) , 10.1021/LA903265P
Liu Deng, Li Shang, Yizhe Wang, Tie Wang, Hongjun Chen, Shaojun Dong, Multilayer structured carbon nanotubes/poly-l-lysine/laccase composite cathode for glucose/O2 biofuel cell Electrochemistry Communications. ,vol. 10, pp. 1012- 1015 ,(2008) , 10.1016/J.ELECOM.2008.05.001
Michael Rodahl, Fredrik Höök, Anatol Krozer, Peter Brzezinski, Bengt Kasemo, Quartz crystal microbalance setup for frequency and Q‐factor measurements in gaseous and liquid environments Review of Scientific Instruments. ,vol. 66, pp. 3924- 3930 ,(1995) , 10.1063/1.1145396
Thomas Crouzier, Catherine Picart, Ion pairing and hydration in polyelectrolyte multilayer films containing polysaccharides. Biomacromolecules. ,vol. 10, pp. 433- 442 ,(2009) , 10.1021/BM8012378
Robert A. Gelman, John Blackwell, Heparin-polypeptide interactions in aqueous solution Archives of Biochemistry and Biophysics. ,vol. 159, pp. 427- 433 ,(1973) , 10.1016/0003-9861(73)90470-0
F. Boulmedais, M. Bozonnet, P. Schwinté, J.-C. Voegel, P. Schaaf, Multilayered polypeptide films: Secondary structures and effect of various stresses Langmuir. ,vol. 19, pp. 9873- 9882 ,(2003) , 10.1021/LA0348259