Fundamentals of Genes and Genomes

作者: Supratim Choudhuri

DOI: 10.1016/B978-0-12-410471-6.00001-3

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摘要: This chapter briefly discusses the structure and function of genes genomes. Some topics covered here are not usually discussed in textbooks molecular biology. The obvious beginning is from double-helical DNA. discussion on hydrogen bonding standard base-pairing principle extended to include Hoogsteen triple helix formation. importance intron phase alternative splicing detail; it lays foundation for understanding exon shuffling during genome evolution, Chapter 2. Various types noncoding RNAs (ncRNAs), such as small ncRNA, long competing endogenous RNA, circular RNA highlighted. chemical basis instability also discussed. relationship between protein location amino acids polypeptide chain explained with examples. important features human characterization its functional elements by Encyclopedia DNA Elements (ENCODE) project A epigenetic modification included.

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