HLA and HIV-1: Heterozygote Advantage and B*35-Cw*04 Disadvantage

作者: Mary Carrington , George W Nelson , Maureen P Martin , Teri Kissner , David Vlahov

DOI: 10.1126/SCIENCE.283.5408.1748

关键词:

摘要: … two copies of the B*35 allele compared with individuals lacking B*35 are shown. RH and corresponding Pvalues are given for the two B*35-bearing genotypes (+/B*35 and B*35/B*35) …

参考文章(55)
Hans Georg Rammensee, Hajime Shiga, Masafumi Takiguchi, Kiyoshi Miwa, Satoshi Kimura, Yuji Takamiya, Takashi Gojoubori, Hiroko Tomiyama, Tatsuo Shioda, Shinichi Oka, Yumi Yamaguchi, Identification of multiple HIV-1 cytotoxic T-cell epitopes presented by human leukocyte antigen B35 molecules AIDS. ,vol. 10, pp. 1075- 1083 ,(1996)
Dominique Charron, HLA : genetic diversity of HLA functional and medical implication EDK Medical and Scientific International ; c1997. ,(1997)
Giorgio Trinchieri, Biology of natural killer cells. Advances in Immunology. ,vol. 47, pp. 187- 376 ,(1989) , 10.1016/S0065-2776(08)60664-1
Sarah Rowland-Jones, Rusung Tan, Andrew McMichael, None, Role of cellular immunity in protection against HIV infection. Advances in Immunology. ,vol. 65, pp. 277- 346 ,(1997) , 10.1016/S0065-2776(08)60745-2
Kathleen L. Collins, Benjamin K. Chen, Spyros A. Kalams, Bruce D. Walker, David Baltimore, HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes Nature. ,vol. 391, pp. 397- 401 ,(1998) , 10.1038/34929
Hajime Shiga, Masafumi Takiguchi, Kiyoshi Miwa, Yutaro Kaneko, Aikichi Iwamoto, Yuki Ikeda Moore, Hiroko Tomiyama, Shinichi Oka, Evidence of presentation of multiple HIV-1 cytotoxic T lymphocyte epitopes by HLA-B*3501 molecules that are associated with the accelerated progression of AIDS. Journal of Immunology. ,vol. 158, pp. 5026- 5034 ,(1997)
P. W. Hedrick, T. S. Whittam, P. Parham, Heterozygosity at individual amino acid sites: Extremely high levels for HLA-A and -B genes Proceedings of the National Academy of Sciences of the United States of America. ,vol. 88, pp. 5897- 5901 ,(1991) , 10.1073/PNAS.88.13.5897
L. H. Boise, C. B. Thompson, Hierarchical Control of Lymphocyte Survival Science. ,vol. 274, pp. 67- 68 ,(1996) , 10.1126/SCIENCE.274.5284.67