Decreased Pain and Improved Quality of Life in Fibromyalgia Patients Treated with Olanzapine, an Atypical Neuroleptic

摘要: Fibromyalgia is a significant clinical problem associated with generalized pain and interference daily activities. Although variety of treatment modalities have been utilized, clinicians struggled to find an effective means treatment. Therefore, this study assessed the efficacy atypical neuroleptic olanzapine for fibromyalgia symptoms. To examine symptoms, charts 51 patients treated were evaluated improvements in life functioning. At time initial assessment, had diagnosed medical psychiatric disorders history Pain was widespread characteristic fibromyalgia. Pretreatment ratings on scales averaged 6.54-8.69 0-10 scale. Post-treatment same revealed improvement virtually all scales. The benefits improve symptoms must, however, be carefully considered because there side effects (i.e., weight gain, somnolence/sedation) that sufficient strength cause number discontinue In general, data provide strong support can, certain patients, who limited success other modalities.