The Promise and Challenges of Developing miRNA-Based Therapeutics for Parkinson's Disease.

作者: Simoneide S. Titze-de-Almeida , Cristina Soto-Sánchez , Eduardo Fernandez , James B. Koprich , Jonathan M. Brotchie

DOI: 10.3390/CELLS9040841

关键词:

摘要: … miRNAs that bind to complementary sequences at 3’-untranslated regions for triggering the mechanism of RNA interference. Unfortunately, dysregulated miRNAs … focus on miRNAs as …

参考文章(234)
Lesly Puspita, Sun Young Chung, Jae-won Shim, Oxidative stress and cellular pathologies in Parkinson's disease. Molecular Brain. ,vol. 10, pp. 53- 53 ,(2017) , 10.1186/S13041-017-0340-9
Yuan Chen, Ya-jun Lian, Yun-qing Ma, Chuan-jie Wu, Ya-ke Zheng, Nan-chang Xie, LncRNA SNHG1 promotes α-synuclein aggregation and toxicity by targeting miR-15b-5p to activate SIAH1 in human neuroblastoma SH-SY5Y cells NeuroToxicology. ,vol. 68, pp. 212- 221 ,(2018) , 10.1016/J.NEURO.2017.12.001
Loredana Leggio, Silvia Vivarelli, Francesca L’Episcopo, Cataldo Tirolo, Salvo Caniglia, Nunzio Testa, Bianca Marchetti, Nunzio Iraci, microRNAs in Parkinson's Disease: From Pathogenesis to Novel Diagnostic and Therapeutic Approaches International Journal of Molecular Sciences. ,vol. 18, pp. 2698- ,(2017) , 10.3390/IJMS18122698
PhilipV Peplow, Bridget Martinez, MicroRNAs in Parkinson's disease and emerging therapeutic targets. Neural Regeneration Research. ,vol. 12, pp. 1945- 1959 ,(2017) , 10.4103/1673-5374.221147
Jose-Alberto Palma, Horacio Kaufmann, Treatment of autonomic dysfunction in Parkinson disease and other synucleinopathies Movement Disorders. ,vol. 33, pp. 372- 390 ,(2018) , 10.1002/MDS.27344
Susanna Mantovani, Simon S. Smith, Richard Gordon, John D. O'Sullivan, An overview of sleep and circadian dysfunction in Parkinson's disease Journal of Sleep Research. ,vol. 27, ,(2018) , 10.1111/JSR.12673
Ricardo Titze-de-Almeida, Simoneide Souza Titze-de-Almeida, miR-7 Replacement Therapy in Parkinson's Disease. Current Gene Therapy. ,vol. 18, pp. 143- 153 ,(2018) , 10.2174/1566523218666180430121323
David Adams, Alejandra Gonzalez-Duarte, William D. O’Riordan, Chih-Chao Yang, Mitsuharu Ueda, Arnt V. Kristen, Ivailo Tournev, Hartmut H. Schmidt, Teresa Coelho, John L. Berk, Kon-Ping Lin, Giuseppe Vita, Shahram Attarian, Violaine Planté-Bordeneuve, Michelle M. Mezei, Josep M. Campistol, Juan Buades, Thomas H. Brannagan, Byoung J. Kim, Jeeyoung Oh, Yesim Parman, Yoshiki Sekijima, Philip N. Hawkins, Scott D. Solomon, Michael Polydefkis, Peter J. Dyck, Pritesh J. Gandhi, Sunita Goyal, Jihong Chen, Andrew L. Strahs, Saraswathy V. Nochur, Marianne T. Sweetser, Pushkal P. Garg, Akshay K. Vaishnaw, Jared A. Gollob, Ole B. Suhr, Patisiran, an RNAi Therapeutic, for Hereditary Transthyretin Amyloidosis The New England Journal of Medicine. ,vol. 379, pp. 11- 21 ,(2018) , 10.1056/NEJMOA1716153
Jacob O'Brien, Heyam Hayder, Yara Zayed, Chun Peng, Overview of MicroRNA Biogenesis, Mechanisms of Actions, and Circulation. Frontiers in Endocrinology. ,vol. 9, pp. 402- 402 ,(2018) , 10.3389/FENDO.2018.00402
Daniel F. Costa, Vladimir P. Torchilin, Micelle-like nanoparticles as siRNA and miRNA carriers for cancer therapy. Biomedical Microdevices. ,vol. 20, pp. 59- ,(2018) , 10.1007/S10544-018-0298-0