Roles of bile acid conjugates and phospholipids in in vitro activation of pancreatic lipase by bear bile and cattle bile

摘要: Abstract Ethnopharmacological relevance Bear bile (BB) originally used as a traditional Chinese medicine has also been adopted in Japan home remedy mainly for gastrointestinal problems due to impaired digestion. However, recently, efforts have made find alternatives BB ecological and ethical reasons. Aims of the study To facilitating fat digestion, we compared potency cattle (CB) or synthetic mixtures major components activate pancreatic lipase with that BB. Materials methods The compositions acid conjugates phospholipids CB were determined by high-performance liquid chromatography thin layer chromatography, respectively. effects well on activity vitro examined. Results contained markedly different types quantities phospholipids, although potencies not significantly different. was reconstituted found In contrast, only could reconstitute its lipase. Conclusions Our observations indicate mixture can be an alternative