Microwave-Assisted and Efficient Solvent-free Knoevenagel Condensation. A Sustainable Protocol Using Porous Calcium Hydroxyapatite as Catalyst
作者： Siham Mallouk , Khalid Bougrin , Abdelaziz Laghzizil , Rachid Benhida
DOI: 10.3390/MOLECULES15020813
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摘要: A sustainable Knoevenagel condensation of a series aldehydes with malononitrile and ethyl cyanoacetate is described. The process based on the combination microwave activation hydroxyapatite catalysis under solvent-free conditions. Products are obtained in high yields after short reaction times. effects specific surface porous calcium discussed.
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