Oxygen-Flow-Pressure Targets for Resuscitation in Critical Hemodynamic Therapy.

作者: Huaiwu He , Yun Long , Xiang Zhou , Xiaoting Wang , Hongmin Zhang

DOI: 10.1097/SHK.0000000000000929

关键词:

摘要: Far from traditional "vital signs," the field of hemodynamic monitoring (HM) is rapidly developing. However, it also easy to misunderstand therapy as merely HM and some concrete bundles or guidelines for circulation support. Here, we describe concept "critical therapy" clarify concepts "therapeutic target" endpoint" in clinical practice. Three main targets (oxygen delivery, blood flow, perfusion pressure) resuscitation are reviewed critically ill patients according sepsis consensus. ScvO2 at least 70% has not been recommended a directed target initial resuscitation, mean arterial pressure (MAP) still 65 mmHg. Moreover, individual MAP underlined, using flow-dependent guide fluid infusion recommended. The flow-directed might be priority, but remains controversial resuscitation. interpretation these necessary adequate correction tissue hypoxia. incoherence phenomenon (macrocirculation microcirculation, perfusion, cellular oxygen utilization) gaining increased attention, early identification incoherences helpful reduce risk over-resuscitation.

参考文章(65)
Matthew R Lammi, Brianne Aiello, Gregory T Burg, Tayyab Rehman, Ivor S Douglas, Arthur P Wheeler, Bennett P deBoisblanc, National Institutes of Health, ARDS Network Investigators, Response to Fluid Boluses in the Fluid and Catheter Treatment Trial Chest. ,vol. 148, pp. 919- 926 ,(2015) , 10.1378/CHEST.15-0445
Can Ince, To beta block or not to beta block; that is the question. Critical Care. ,vol. 19, pp. 339- 339 ,(2015) , 10.1186/S13054-015-1059-6
Huaiwu He, Dawei Liu, Fluid bolus therapy is a medical therapy or a diagnostic method Critical Care. ,vol. 19, pp. 360- 360 ,(2015) , 10.1186/S13054-015-1078-3
Martin Dres, Xavier Monnet, Jean-Louis Teboul, Hemodynamic management of cardiovascular failure by using PCO 2 venous-arterial difference Journal of Clinical Monitoring and Computing. ,vol. 26, pp. 367- 374 ,(2012) , 10.1007/S10877-012-9381-X
William C. Shoemaker, Physiologic Patterns in Surviving and Nonsurviving Shock Patients Archives of Surgery. ,vol. 106, pp. 630- 636 ,(1973) , 10.1001/ARCHSURG.1973.01350170004003
David Schnell, Laurent Camous, Stéphane Guyomarc’h, Jacques Duranteau, Emmanuel Canet, Pierre Gery, Anne-Sylvie Dumenil, Fabrice Zeni, Elie Azoulay, Michael Darmon, Renal perfusion assessment by renal Doppler during fluid challenge in sepsis. Critical Care Medicine. ,vol. 41, pp. 1214- 1220 ,(2013) , 10.1097/CCM.0B013E31827C0A36
Giuseppe Natalini, Antonio Rosano, Carmine Rocco Militano, Antonella Di Maio, Pierluigi Ferretti, Michele Bertelli, Federica de Giuli, Achille Bernardini, Prediction of arterial pressure increase after fluid challenge BMC Anesthesiology. ,vol. 12, pp. 3- 3 ,(2012) , 10.1186/1471-2253-12-3
Jaume Mesquida, Paula Saludes, Guillem Gruartmoner, Cristina Espinal, Eva Torrents, Francisco Baigorri, Antonio Artigas, Central venous-to-arterial carbon dioxide difference combined with arterial-to-venous oxygen content difference is associated with lactate evolution in the hemodynamic resuscitation process in early septic shock Critical Care. ,vol. 19, pp. 126- 126 ,(2015) , 10.1186/S13054-015-0858-0
Alexandre Lima, Jasper van Bommel, Karolina Sikorska, Michel van Genderen, Eva Klijn, Emmanuel Lesaffre, Can Ince, Jan Bakker, The relation of near-infrared spectroscopy with changes in peripheral circulation in critically ill patients Critical Care Medicine. ,vol. 39, pp. 1649- 1654 ,(2011) , 10.1097/CCM.0B013E3182186675