Apoptosis induced by the lymphocyte effector molecule perforin.

作者: P BOLITHO , I VOSKOBOINIK , J TRAPANI , M SMYTH

DOI: 10.1016/J.COI.2007.04.007

关键词:

摘要: … the uptake and cytotoxic activity of granzyme B, but has no … activities of NK cells were mediated by perforin rather than by … suggested that granzyme B, but not perforin, is one of the key …

参考文章(73)
Ling Ling Ma, Christopher L. C. Wang, Graham G. Neely, Slava Epelman, Alan M. Krensky, Christopher H. Mody, NK cells use perforin rather than granulysin for anticryptococcal activity Journal of Immunology. ,vol. 173, pp. 3357- 3365 ,(2004) , 10.4049/JIMMUNOL.173.5.3357
Josianne Nitcheu, Olivia Bonduelle, Christophe Combadiere, Maurel Tefit, Danielle Seilhean, Dominique Mazier, Behazine Combadiere, Perforin-Dependent Brain-Infiltrating Cytotoxic CD8+ T Lymphocytes Mediate Experimental Cerebral Malaria Pathogenesis The Journal of Immunology. ,vol. 170, pp. 2221- 2228 ,(2003) , 10.4049/JIMMUNOL.170.4.2221
Arno Müllbacher, Ron Tha Hla, Crisan Museteanu, Markus M. Simon, Perforin Is Essential for Control of Ectromelia Virus but Not Related Poxviruses in Mice Journal of Virology. ,vol. 73, pp. 1665- 1667 ,(1999) , 10.1128/JVI.73.2.1665-1667.1999
David C. Gondek, Li-Fan Lu, Sergio A. Quezada, Shimon Sakaguchi, Randolph J. Noelle, Cutting Edge: Contact-Mediated Suppression by CD4+CD25+ Regulatory Cells Involves a Granzyme B-Dependent, Perforin-Independent Mechanism Journal of Immunology. ,vol. 174, pp. 1783- 1786 ,(2005) , 10.4049/JIMMUNOL.174.4.1783
Hongxia Lu, Qiang Hou, Tongbiao Zhao, Honglian Zhang, Qixiang Zhang, Lianfeng Wu, Zusen Fan, Granzyme M Directly Cleaves Inhibitor of Caspase-Activated DNase (CAD) to Unleash CAD Leading to DNA Fragmentation Journal of Immunology. ,vol. 177, pp. 1171- 1178 ,(2006) , 10.4049/JIMMUNOL.177.2.1171
Manisha Gupta, Patricia Greer, Siddhartha Mahanty, Wun-Ju Shieh, Sherif R Zaki, Rafi Ahmed, Pierre E Rollin, None, CD8-mediated protection against Ebola virus infection is perforin dependent. Journal of Immunology. ,vol. 174, pp. 4198- 4202 ,(2005) , 10.4049/JIMMUNOL.174.7.4198
Mark J. Smyth, Masaru Taniguchi, Shayna E. A. Street, The Anti-Tumor Activity of IL-12: Mechanisms of Innate Immunity That Are Model and Dose Dependent Journal of Immunology. ,vol. 165, pp. 2665- 2670 ,(2000) , 10.4049/JIMMUNOL.165.5.2665
Jason Brady, Yoshihiro Hayakawa, Mark J. Smyth, Stephen L. Nutt, IL-21 Induces the Functional Maturation of Murine NK Cells Journal of Immunology. ,vol. 172, pp. 2048- 2058 ,(2004) , 10.4049/JIMMUNOL.172.4.2048
Anthony A. Scalzo, Marie B. Snook, Kevin Y. T. Thia, Janice M. Kelly, Catherine A. Forbes, Mark J. Smyth, Erika Cretney, Perforin is a major contributor to NK cell control of tumor metastasis Journal of Immunology. ,vol. 162, pp. 6658- 6662 ,(1999)
Dipanjan Chowdhury, Paul J. Beresford, Pengcheng Zhu, Dong Zhang, Jung-Suk Sung, Bruce Demple, Fred W. Perrino, Judy Lieberman, The exonuclease TREX1 is in the SET complex and acts in concert with NM23-H1 to degrade DNA during granzyme A-mediated cell death. Molecular Cell. ,vol. 23, pp. 133- 142 ,(2006) , 10.1016/J.MOLCEL.2006.06.005