Opioid peptides and their receptors.
作者： H.W. Kosterlitz , S.J. Paterson , L.E. Robson
DOI: 10.1016/B978-0-08-028021-9.50005-8
关键词:
摘要: The three agonists, methionine-enkephalin, leucine-enkephalin and beta-endorphin have different pharmacological patterns. It may be of particular importance that they vary in their relative affinities to the enkephalin naltrexone binding sites brain; former are probably related delta-receptors prevalent mouse vas deferens later mu-receptors guinea-pig. is possible more important for mediation analgesic effects than delta-receptors. An understanding pharmacokinetics opioid peptides will basic design analogues suitable use as analgesics man.
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