Inhibition of tumor size by streptozotocin-induced diabetes mellitus.
作者： Gerald M. Sloan , Len C. Harrison , Lisa H. Underhill , Murray F. Brennan
DOI: 10.1016/0022-4804(81)90091-3
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摘要: Abstract The effects of experimental diabetes mellitus on tumor growth were studied. Male Fischer rats rendered diabetic with a single intravenous injection streptozotocin. Ten days later they inoculated 10 6 cells methylcholanthrene-induced sarcoma, and was observed for 28 days. In three consecutive experiments selectively inhibited size at Day following inoculation, by 65% ( n = 24, P 30, 54, r −0.80,
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