The role of T cells in the microenvironment of Hodgkin lymphoma

作者: Frederik Wein , Ralf Küppers

DOI: 10.1189/JLB.3MR0315-136R

关键词:

摘要: The cellular microenvironment in HL is dominated by a mixed infiltrate of inflammatory cells with typically only 1 or few percent HRS tumor cells. orchestrate this the secretion multitude chemokines. T are usually largest population tissue, encompassing Th cells, T(regs), and CTLs. T(regs) presumably provide essential survival signals for also play an important role rescuing from attack CTLs NK interference complex interplay other immune may novel strategies targeted immunotherapies.

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