Mass Spectrometric Studies of Cocaine Disposition in Animals and Humans Using Stable Isotope-Labeled Analogues

作者: Satya P. Jindal , Theresa Lutz

DOI: 10.1002/JPS.2600781208

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摘要: … in vivo use of stable isotope-labeled analogues to explore the biotransformation of cocaine. In … The TIC trace shows five distinct peaks, while the SIM trace shows three peaks coincident …

参考文章(31)
Carl-Gustaf Hammar, Bo Holmstedt, Ragnar Ryhage, Mass fragmentography Analytical Biochemistry. ,vol. 25, pp. 532- 548 ,(1968) , 10.1016/0003-2697(68)90131-0
Roger C. Parish, Leon M. Stock, A Method for the Esterification of Hindered Acids1 Journal of Organic Chemistry. ,vol. 30, pp. 927- 929 ,(1965) , 10.1021/JO01014A066
Sakti P. Bagghi, Thomas M. Smith, Preeti Bagchi, Divergent reserpine effects on amfonelic acid and amphetamine stimulation of synaptosomal dopamine formation from phenylalanine. Biochemical Pharmacology. ,vol. 29, pp. 2957- 2962 ,(1980) , 10.1016/0006-2952(80)90044-1
D.R. Knapp, T.E. Gaffney, R.E. McMahon, Use of stable isotope mixtures as a labeling technique in drug metabolism studies. Biochemical Pharmacology. ,vol. 21, pp. 425- 429 ,(1972) , 10.1016/0006-2952(72)90357-7
Satya P. Jindal, Theresa Lutz, Per Vestergaard, Mass spectrometric determination of cocaine and its biologically active metabolite, norcocaine, in human urine Journal of Mass Spectrometry. ,vol. 5, pp. 658- 663 ,(1978) , 10.1002/BMS.1200051205
Mahmoud A. ElSohly, Donald F. Stanford, Hala N. ElSohly, Coca tea and urinalysis for cocaine metabolites. Journal of Analytical Toxicology. ,vol. 10, pp. 256- 256 ,(1986) , 10.1093/JAT/10.6.256
William J. A. VandenHeuvel, Drug Metabolite Identification: Stable Isotope Methods The Journal of Clinical Pharmacology. ,vol. 26, pp. 427- 434 ,(1986) , 10.1002/J.1552-4604.1986.TB03553.X