Manufacturing of human placenta-derived mesenchymal stem cells for clinical trials.
作者： Gary Brooke , Tony Rossetti , Rebecca Pelekanos , Nina Ilic , Patricia Murray
DOI: 10.1111/J.1365-2141.2008.07492.X
关键词:
摘要: Mesenchymal stem cells (MSC) are being used increasingly in clinical trials for a range of regenerative and inflammatory diseases. Bone marrow is the traditional source but relatively inaccessible large volume. MSC have now been derived from tissues other than bone including placenta adipose tissue. We obtained after delivery as unable to detect any marked differences marrow-derived terms cell surface phenotype, chemokine receptor display, mesodermal differentiation capacity or immunosuppressive ability. This report described our manufacturing process isolating expanding placenta-derived human their safe infusion into first patient trial program MSC.
core.ac.uk
uq.edu.au参考文章(28)
Maureen Owen, A. J. Friedenstein, Stromal Stem Cells: Marrow‐Derived Osteogenic Precursors Ciba Foundation Symposium. ,vol. 136, pp. 42- 60 ,(1988) , 10.1002/9780470513637.CH4
Kuan-Der Lee, Tom Kwang-Chun Kuo, Jacqueline Whang-Peng, Yu-Fen Chung, Ching-Tai Lin, Shiu-Huey Chou, Jim-Ray Chen, Yi-Peng Chen, Oscar Kuang-Sheng Lee, In vitro hepatic differentiation of human mesenchymal stem cells Hepatology. ,vol. 40, pp. 1275- 1284 ,(2004) , 10.1002/HEP.20469
Alejandro Erices, Paulette Conget, José J. Minguell, Mesenchymal progenitor cells in human umbilical cord blood. British Journal of Haematology. ,vol. 109, pp. 235- 242 ,(2000) , 10.1046/J.1365-2141.2000.01986.X
B. Linju Yen, Hsing-I Huang, Chih-Cheng Chien, Hsiang-Yiang Jui, Bor-Sheng Ko, Ming Yao, Chia-Tung Shun, Men-luh Yen, Meng-Chou Lee, Yao-Chang Chen, Isolation of multipotent cells from human term placenta. Stem Cells. ,vol. 23, pp. 3- 9 ,(2005) , 10.1634/STEMCELLS.2004-0098
Oscar K. Lee, Tom K. Kuo, Wei-Ming Chen, Kuan-Der Lee, Shie-Liang Hsieh, Tain-Hsiung Chen, Isolation of multipotent mesenchymal stem cells from umbilical cord blood. Blood. ,vol. 103, pp. 1669- 1675 ,(2004) , 10.1182/BLOOD-2003-05-1670
Shinji Tomita, Donald A.G. Mickle, Richard D. Weisel, Zhi-Qiang Jia, Laura C. Tumiati, Yasmin Allidina, Peter Liu, Ren-Ke Li, Improved heart function with myogenesis and angiogenesis after autologous porcine bone marrow stromal cell transplantation. The Journal of Thoracic and Cardiovascular Surgery. ,vol. 123, pp. 1132- 1140 ,(2002) , 10.1067/MTC.2002.120716
Hwai-Shi Wang, Shih-Chieh Hung, Shu-Tine Peng, Chun-Chieh Huang, Hung-Mu Wei, Yi-Jhih Guo, Yu-Show Fu, Mei-Chun Lai, Chin-Chang Chen, Mesenchymal Stem Cells in the Wharton's Jelly of the Human Umbilical Cord Stem Cells. ,vol. 22, pp. 1330- 1337 ,(2004) , 10.1634/STEMCELLS.2004-0013
Gary Brooke, Hui Tong, Jean-Pierre Levesque, Kerry Atkinson, Molecular trafficking mechanisms of multipotent mesenchymal stem cells derived from human bone marrow and placenta. Stem Cells and Development. ,vol. 17, pp. 929- 940 ,(2008) , 10.1089/SCD.2007.0156
Gary Brooke, Matthew Cook, Chris Blair, Rachel Han, Celena Heazlewood, Ben Jones, Melinda Kambouris, Kate Kollar, Steven McTaggart, Rebecca Pelekanos, Alison Rice, Tony Rossetti, Kerry Atkinson, Therapeutic applications of mesenchymal stromal cells. Seminars in Cell & Developmental Biology. ,vol. 18, pp. 846- 858 ,(2007) , 10.1016/J.SEMCDB.2007.09.012
Domizio Suva, Guido Garavaglia, Jacques Menetrey, Bernard Chapuis, Pierre Hoffmeyer, Laurent Bernheim, Vincent Kindler, Non-hematopoietic human bone marrow contains long-lasting, pluripotential mesenchymal stem cells. Journal of Cellular Physiology. ,vol. 198, pp. 110- 118 ,(2004) , 10.1002/JCP.10396