Acute Asthma in Children and Adolescents

摘要: Children and adolescents experiencing acute exacerbations of asthma benefit from the use beta(2)-adrenoceptor agonists (beta(2)-agonists) systemic corticosteroids. However, there have been conflicting reports regarding efficacy inhaled anticholinergic agents. This article summarizes evidence provided by randomized controlled trials studying adding agents to beta(2)-agonists in nonhospitalized children with asthma. systematic review suggests that addition is beneficial adolescents, particularly those severe When given repeated doses, improves lung function reduces risk hospital admission 25%. Several treatment regimens, namely ipratropium bromide (250 or 500 microg per dose) every 20-60 minutes for two three doses tested similar effects. The a single dose an agent but does not prevent admission. did identify any effects nonsevere Use was associated increase incidence nausea, vomiting tremor. In conclusion, beta(2)-agonist indicated emergency room management asthma, exacerbations.