Accumulation of amylase by chick pancreas in organ culture: Effect of hydrocortisone

作者: U. Yalovsky , H. Heller , R.G. Kulka

DOI: 10.1016/0014-4827(73)90303-0

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摘要: Abstract Accumulation of amylase by pancreas explants from chick embryos 7 to 14 days development was studied in organ culture. The produced but there no increase their total DNA and little if any protein. Most the cultures released into culture medium. lower developmental age at which taken, greater relative activity After several accumulation slowed or stopped. Hydrocortisone markedly increased amount explants. hormone had effect on initial rate However, addition hydrocortisone resulted a continuing when enzyme ceased controls without added hormone. observations support hypothesis, suggested earlier, that corticosteroid hormones are implicated later stages differentiation embryonic pancreas.

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