Accumulation of hydrogen peroxide is an early and crucial step for paclitaxel-induced cancer cell death both in vitro and in vivo.
作者： Jérôme Alexandre , Frédéric Batteux , Carole Nicco , Christiane Chéreau , Alexis Laurent
DOI: 10.1002/IJC.21685
关键词:
摘要: … of ROS in A549 human lung cancer cells exposed in vitro to paclitaxel and investigated the consequences of its inhibition both in vitro and in vivo. We found that H 2 O 2 accumulation is …
sci-hub.se 参考文章(51)
Jie Dai, Rona S. Weinberg, Samuel Waxman, Yongkui Jing, Malignant Cells Can Be Sensitized to Undergo Growth Inhibition and Apoptosis by Arsenic Trioxide Through Modulation of the Glutathione Redox System Blood. ,vol. 93, pp. 268- 277 ,(1999) , 10.1182/BLOOD.V93.1.268
Tito Fojo, Susan E. Bates, Robert Robey, Mikhail V. Blagosklonny, Philippe C. Bishop, Loss of cell cycle control allows selective microtubule-active drug-induced Bcl-2 phosphorylation and cytotoxicity in autonomous cancer cells. Cancer Research. ,vol. 60, pp. 3425- 3428 ,(2000)
Min Liang Kuo, Shine Gwo Shiah, Shing Chuan Shen, Shuang En Chuang, Yat Pang Chau, Activation of c-Jun NH2-terminal Kinase and Subsequent CPP32/Yama during Topoisomerase Inhibitor β-Lapachone-induced Apoptosis through an Oxidation-dependent Pathway Cancer Research. ,vol. 59, pp. 391- 398 ,(1999)
Thomas C. Chiles, Shashi R. Mehta, Stephen F. Amato, Jennifer M. Swart, Harold J. Wanebo, Melissa Berg, Transient stimulation of the c-Jun-NH2-terminal kinase/activator protein 1 pathway and inhibition of extracellular signal-regulated kinase are early effects in paclitaxel-mediated apoptosis in human B lymphoblasts. Cancer Research. ,vol. 58, pp. 241- 247 ,(1998)
Susan Band Horwitz, Jie Guang Chen, Differential Mitotic Responses to Microtubule-stabilizing and -destabilizing Drugs Cancer Research. ,vol. 62, pp. 1935- 1938 ,(2002)
K. W. Kohn, D. J. Rivet, A. J. Fornace, Qimin Zhan, M. L. Smith, Saijun Fan, P. M. O'connor, D. Duba, Disruption of p53 Function Sensitizes Breast Cancer MCF-7 Cells to Cisplatin and Pentoxifylline Cancer Research. ,vol. 55, pp. 1649- 1654 ,(1995)
Hayley M. McDaid, Thomas R.R. Pettus, Laura A. Martello, Susan Band Horwitz, Donna Lee Regl, Hirokazu Arimoto, Amos B. Smith, Michael D. Kaufman, Samuel J. Danishefsky, Chia Ping H. Yang, Dongfang Meng, Taxol and Discodermolide Represent a Synergistic Drug Combination in Human Carcinoma Cell Lines Clinical Cancer Research. ,vol. 6, pp. 1978- 1987 ,(2000)
Paul M. Hwang, Fred Bunz, Jian Yu, Carlo Rago, Timothy A. Chan, Michael P. Murphy, Geoffry F. Kelso, Robin A. J. Smith, Kenneth W. Kinzler, Bert Vogelstein, Ferredoxin reductase affects p53-dependent, 5-fluorouracil–induced apoptosis in colorectal cancer cells Nature Medicine. ,vol. 7, pp. 1111- 1117 ,(2001) , 10.1038/NM1001-1111
Wendell K, Jordan Ma, Wilson L, Copp H, Gardiner S, Derry Wb, Mitotic Block Induced in HeLa Cells by Low Concentrations of Paclitaxel (Taxol) Results in Abnormal Mitotic Exit and Apoptotic Cell Death Cancer Research. ,vol. 56, pp. 816- 825 ,(1996)
Keila Enitt Torres, Susan Band Horwitz, Mechanisms of taxol-induced cell death are concentration dependent Cancer Research. ,vol. 58, pp. 3620- 3626 ,(1998)