Angiotensinogen gene polymorphisms and progression of chronic kidney disease in ADPKD patients

作者: Ramanathan Gnanasambandan , Ramprasad Elumalai , Periyasamy Soundararajan , Bhaskar VKS Lakkakula , None

DOI: 10.1007/S10157-015-1183-2

关键词:

摘要: Background Autosomal dominant polycystic kidney disease (ADPKD) is a multisystemic and progressive disorder characterized by cyst formation enlargement ultimately renal failure. Reduction of CKD progression in the ADPKD pharmacological blockade renin–angiotensin–aldosterone system (RAAS) using ACE inhibitors indicated involvement RAAS pathway CKD. The aim present study to investigate role angiotensinogen tag-single nucleotide polymorphisms (AGT tag-SNPs)

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