Mechanoresponsive system based on sub-micron chitosan-functionalized ferromagnetic disks
作者： Dong-Hyun Kim , Pavel Karavayev , Elena A. Rozhkova , John Pearson , Volodymyr Yefremenko
DOI: 10.1039/C1JM10272A
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摘要: We report a doxorubicin loaded chitosan biopolymer–ferromagnetic disks hybrid system capable of on-demand magnetomechanically induced release drug molecules. Gold covered ferromagnetic were encapsulated into the polymer scaffold through assembly thiolated on disk's gold surface followed by entrapping within cross-linked matrix. demonstrate that process can be effectively tuned and controlled varying magnetic field characteristics: orientation, amplitude, frequency duration.
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