Information Transfer and Sperm Uptake by Mammalian Somatic Cells

摘要: Publisher Summary This chapter describes that sperm are endowed by their specific differentiation to interact with and deliver genetic components into ova for subsequent activation function. Whether analogous information can be transferred mammalian somatic cells is unknown. The as evidenced actual penetration, the appearance of changes in morphology growth characteristics, production new gene products. These may consequences direct acquisition expression either chromatin itself or reverse transcriptase containing complex within heads. interaction leads fetal antigen resembling oncogenic transformation involve a recapitulation, at least part, program postfertilization expression. normal function fertilization; presence its various might very well induce those occur embryological development. It has been estimated amount unique-sequence DNA transcribed rabbit blastocyst but no longer midgestation embryo enough specify some 23,000 different proteins; corresponding difference between virus-transformed mouse regarded sufficient 200,000 proteins. To sort out many steps involved embryogenesis, development, oncogenesis face such complexity indeed prodigious task.