Destruction of intracerebrally applied red blood cells in cervical lymph nodes. Experimental investigations.

作者: Manfred Oehmichen , Horst Wiethölter , Helmut Grüninger , Mira Gencic

DOI: 10.1016/0379-0738(83)90089-0

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摘要: In rabbits, intracerebrally applied erythrocytes can move with the cerebrospinal fluid along connecting pathways between subarachnoid space and cervical lymph nodes. This study compares time dependency for degradation of injected in brain as well Rabbits were killed at various predetermined intervals after intracerebral erythrocyte injection. Microscopic histologic examination nodes revealed following findings: (1) Erythrophages first appeared 24 h injection; siderophages, 4 days Siderophages still demonstrable conclusion study, i.e. 240 (2) erythrophages observed 1 9 Only isolated siderophages found 12 injection red blood cells. Later on no or The findings indicate that non-phagocytized cells arriving ingested by local macrophages. extremely rapid ingestion digestion node macrophages possible reasons discussed.

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