Probiotic administration effect on fecal mutagenicity and microflora in the goat's gut.
作者： Ana Lidia Apás , Javier Dupraz , Romina Ross , Silvia Nelina González , Mario Eduardo Arena
DOI: 10.1016/J.JBIOSC.2010.06.005
关键词:
摘要: The application of potentially beneficial microorganisms to increase host defense is a new trend health benefits. In this paper the first specific probiotics for goats from mixture isolated healthy animals (Lactobacillus reuteri DDL 19, Lactobacillus alimentarius 48, Enterococcus faecium DDE 39 and Bifidobacterium bifidum DDBA) was assayed. effect probiotic oral administration on goats' weight, gut microbiota, as well production mutagen compounds their indicator (putrescine), were evaluated. supplement able modify microflora balance by reducing Enterobacteria like Salmonella/Shigella (1.09 1.21 log CFU/g feces, respectively) increasing lactic acid bacteria Bifidobacteria (1.67 2.34 respectively). correlated with ten time diminution fecal putrescine (cancer bacterial disease marker) decrease 60% concentration, indicating protective treatment. Additionally, significant in ruminant weight observed after administration. These results are encouraging towards use mixtures functional food goats.
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B. Jensen, The impact of feed additives on the microbial ecology of the gut in young pigs Journal of Animal and Feed Sciences. ,vol. 7, pp. 45- 64 ,(1998) , 10.22358/JAFS/69955/1998
Pawel Janczyk, Robert Pieper, Hauke Smidt, Wolfgang Bernhard Souffrant, Changes in the diversity of pig ileal lactobacilli around weaning determined by means of 16S rRNA gene amplification and denaturing gradient gel electrophoresis FEMS Microbiology Ecology. ,vol. 61, pp. 132- 140 ,(2007) , 10.1111/J.1574-6941.2007.00317.X
Thresia Thomas, T. J. Thomas, Polyamine metabolism and cancer Journal of Cellular and Molecular Medicine. ,vol. 7, pp. 113- 126 ,(2003) , 10.1111/J.1582-4934.2003.TB00210.X
Diana Teti, Maria Visalli, Harold McNair, Analysis of polyamines as markers of (patho)physiological conditions. Journal of Chromatography B. ,vol. 781, pp. 107- 149 ,(2002) , 10.1016/S1570-0232(02)00669-4
Dorothy M. Maron, Bruce N. Ames, REVISED METHODS FOR THE SALMONELLA MUTAGENICITY TEST Mutation Research. ,vol. 113, pp. 173- 215 ,(1983) , 10.1016/0165-1161(83)90010-9
Nikolaus Seiler, Thirty years of polyamine-related approaches to cancer therapy. Retrospect and prospect. Part 2. Structural analogues and derivatives. Current Drug Targets. ,vol. 4, pp. 565- 585 ,(2003) , 10.2174/1389450033490876
Robert W. Chadwick, S. Elizabeth George, Larry D. Claxton, Role of the Gastrointestinal Mucosa and Microflora in the Bioactivation of Dietary and Environmental Mutagens or Carcinogens Drug Metabolism Reviews. ,vol. 24, pp. 425- 492 ,(1992) , 10.3109/03602539208996302
Nikolaus Seiler, Thirty Years of Polyamine-Related Approaches to Cancer Therapy. Retrospect and Prospect. Part 1. Selective Enzyme Inhibitors Current Drug Targets. ,vol. 4, pp. 537- 564 ,(2003) , 10.2174/1389450033490885
Robert Pieper, Pawel Janczyk, Annette Zeyner, Hauke Smidt, Volker Guiard, Wolfgang Bernhard Souffrant, Ecophysiology of the Developing Total Bacterial and Lactobacillus Communities in the Terminal Small Intestine of Weaning Piglets Microbial Ecology. ,vol. 56, pp. 474- 483 ,(2008) , 10.1007/S00248-008-9366-Y
J.R. Pluske, B. Black, D.W. Pethick, B.P. Mullan, D.J. Hampson, Effects of different sources and levels of dietary fibre in diets on performance, digesta characteristics and antibiotic treatment of pigs after weaning Animal Feed Science and Technology. ,vol. 107, pp. 129- 142 ,(2003) , 10.1016/S0377-8401(03)00072-5