作者: Mara E.J. Bouwmans , Elisabeth H. Bos , H.J. Rogier Hoenders , Albertine J. Oldehinkel , Peter de Jonge
DOI: 10.1016/J.JAD.2016.09.046
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摘要: Background: The exact nature of the complex relationship between sleep and affect has remained unclear. This study investigated temporal order change in participants with without depression. Methods: 27 depressed patients pair-matched healthy controls assessed their morning am 3 times a day for 30 consecutive days natural environment. Daily quality average, positive (PA) negative (NA) were used to examine whether changes preceded or followed PA NA, this was different controls. Second. presumptive mediating factors investigated. We hypothesized that fatigue mediated effect on subsequent PA/NA, rumination PA/NA quality. Results: Multilevel models showed predicted (B=0.08, p <0.001: NA (B=-0.06, <0.001), but not other way around (PA: B=0.03, p=0.70, NA: B=-0.05, p=0.60). Fatigue found be significant mediator (Indirect Effect=0.03, Effect=-0.02, p=0.01). Rumination no because non-significant associations Limitations: analyses restricted self-reported quality, conclusions about causality could drawn. Conclusions: Improvements improvements following day, partly by fatigue. Treatment symptoms would benefit clinical care beyond.