Genes of innate immunity and the biological response to inhaled ozone

摘要: Ambient ozone has a significant impact on human health. We have made considerable progress in understanding the fundamental mechanisms that regulate biological response to ozone. It is increasingly clear genes of innate immunity play central role both infectious and noninfectious lung disease. The ambient provides clinically relevant environmental exposure allows us better understand airways In this brief review, we focus (1) specific cell types modified by ozone, (2) oxidative stress, (3) relationship between (4) extracellular matrix reactive disease, (5) effect adaptive immune system. summarize recent advances contributes