Comparative Study of High-Resolution CT Findings Between Autoimmune and Secondary Pulmonary Alveolar Proteinosis
作者： Haruyuki Ishii , Bruce C Trapnell , Ryushi Tazawa , Yoshikazu Inoue , Masanori Akira
关键词:
摘要: Background Acquired pulmonary alveolar proteinosis (PAP) has been reclassified into autoimmune or secondary PAP according to the occurrence of serum granulocyte macrophage colony-stimulating factor autoantibody. Most patients undergo high-resolution CT (HRCT) scanning in order for physicians make a differential diagnosis diffuse lung diseases, but no information is available distinguish HRCT scan features from those PAP. The objective this study was characterize and Methods scans 42 (21 each groups) were centrally collected evaluated blinded manner. Results Ground-glass opacities (GGO) major finding both groups. In group, GGOs typically showed pattern (62%), whereas patchy geographic group (71%; p Conclusions Typical findings GGO with pattern, subpleural sparing, crazy-paving appearance, predominance lower field. These rather infrequent patients.
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