Joint tobacco smoking and alcohol intake exacerbates cancer risk in women- the Danish nurse cohort.

作者: Jette Heberg , Mette Kildevæld Simonsen , Anne Kjaergaard Danielsen , Tobias Wirenfeldt Klausen , Vibeke Zoffmann

DOI: 10.1016/J.EJON.2019.101675

关键词:

摘要: Abstract Purpose To explore separate and combined tobacco alcohol use risk of overall, smoking-related, alcohol-related, breast gynecological cancers in women. Method Questionnaires from 19,898 women The Danish Nurse Cohort 1993 were linked to registries on hospitalizations, death causes migration until Dec 2016. Cancer by was estimated using Cox proportional hazards models. Results 16,106 nurses, aged >44 years (mean = 56), eligible for analysis. Throughout 23 (mean follow-up = 18.8 years) overall counted 4,968. Of these, 1,897, 2,231, 1,407 579 events cancers. Increased risks cancer observed current smoking excess intake (>14 units/week), separately, compared never light drinking (1–7 units/week) respectively. Moderate (8–14 increased the alcohol-related cancer. Additional increases among smokers above levels (HR = 1.40, 95% CI:1.30–1.51, HR = 1.72, CI:1.52–1.94, HR = 1.33, CI:1.26–1.40, HR = 1.32, CI:1.15–1.53, respectively), non-smokers lightly. These further moderate (HR = 1.49, CI:1.36–1.63, HR = 1.97, CI:171.-2.26, HR = 1.40, CI:1.22–1.60, CI:1.12–1.57, respectively). No significant associations found Conclusions Smoking alcohol, both separately combined, cancer; resulted incremental increases. Co-use represent an extensive threat public health; thus, prevention could benefit targeting.

参考文章(48)
H Forouzanfar Mohammad, Afshin Ashkan, T Alexander Lily, H Ross Anderson, A Bhutta Zulfiqar, Biryukov Stan, Brauer Michael, Burnett Richard, Cercy Kelly, J Charlson Fiona, J Cohen Aaron, Dandona Lalit, Estep Kara, J Ferrari Alize, J Frostad Joseph, Fullman Nancy, W Gething Peter, W Godwin William, Griswold Max, Kinfu Yohannes, H Kyu Hmwe, J Larson Heidi, Liang Xiaofeng, S Lim Stephen, Y Liu Patrick, D Lopez Alan, Lozano Rafael, Marczak Laurie, A Mensah George, Mokdad Ali H, Moradi Lakeh Maziar, Naghavi Mohsen, Neal Bruce, B Reitsma Marissa, Roth Gregory A, A Salomon Joshua, J Sur Patrick, Vos Theo, Wagner Joseph A, Wang Haidong, Yi Zhao, Zhou Maigeng, Marit Aasvang Gunn, Alemu Abajobir Amanuel, Hassen Abate Kalkidan, Abbafati Cristiana, M Abbas Kaja, Abd Allah Foad, M Abdulle Abdishakur, Ferede Abera Semaw, Abraham Biju, J Laith, Yitayih Abyu Gebre, Olupelumi Adebiyi Akindele, Akinkunmi Adedeji Isaac, Ademi Zanfina, Kouablan Adou Arsène, C Adsuar José, Elisabet Agardh Emilie, Agarwal Arnav, Agrawal Anurag, Ahmad Kiadaliri Aliasghar, N Ajala Oluremi, F Akinyemiju Tomi, Al Aly Ziyad, Alam Khurshid, KM Noore, Fahed Aldhahri Saleh, William Aldridge Robert, Aderaw Alemu Zewdie, Ali Raghib, Alkerwi Ala'A, Alla François, Allebeck Peter, Alsharif Ubai, A Altirkawi Khalid, Alvarez Martin Elena, Alvis Guzman Nelson, T Amare Azmeraw, Amberbir Alemayehu, Kofi Amegah Adeladza, Amini Heresh, Ammar Walid, Marc Amrock Stephen, H Andersen Hjalte, O Anderson Benjamin, Abelardo T Antonio Carl, Anwari Palwasha, Ärnlöv Johan, Al Artaman, Asayesh Hamid, Jawad Asghar Rana, Assadi Reza, Atique Suleman, Frinel G Euripide, Awasthi Ashish, Paulina Ayala Quintanilla Beatriz, Azzopardi Peter, Bacha Umar, Badawi Alaa, Bahit Maria C, Balakrishnan Kalpana, Barac Aleksandra, M Barber Ryan, L Suzanne, Bärnighausen Till, Barquera Simon, Barregard Lars, Barrero Lope H, Basu Sanjay, Batis Carolina, Bazargan Hejazi Shahrzad, Beardsley Justin, Bedi Neeraj, Beghi Ettore, L Bell Michelle, K Bello Aminu, A Bennett Derrick, M Bensenor Isabela, Berhane Adugnaw, Bernabé Eduardo, Demtsu Betsu Balem, Shunu Beyene Addisu, Bhala Neeraj, Bhansali Anil, Bhatt Samir, Biadgilign Sibhatu, Bikbov Boris, Bisanzio Donal, Bjertness Espen, D Blore Jed, Borschmann Rohan, Boufous Soufiane, RA Rupert, Brainin Michael, Brazinova Alexandra, JK Nicholas, Brenner Hermann, Broday David M, S Brugha Traolach, Brunekreef Bert, A Butt Zahid, E Cahill Leah, Calabria Bianca, Ricardo Campos Nonato Ismael, Cárdenas Rosario, Carpenter David O, Casey Daniel C, Castañeda Orjuela Carlos A, Castillo Rivas Jacqueline, None, Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015 The Lancet. ,vol. 388, pp. 1659- 1724 ,(2016) , 10.1016/S0140-6736(16)31679-8
Andrew Smyth, Koon K Teo, Sumathy Rangarajan, Martin O'Donnell, Xiaohe Zhang, Punam Rana, Darryl P Leong, Gilles Dagenais, Pamela Seron, Annika Rosengren, Aletta E Schutte, Patricio Lopez-Jaramillo, Ayetkin Oguz, Jephat Chifamba, Rafael Diaz, Scott Lear, Alvaro Avezum, Rajesh Kumar, Viswanathan Mohan, Andrzej Szuba, Li Wei, Wang Yang, Bo Jian, Martin McKee, Salim Yusuf, None, Alcohol consumption and cardiovascular disease, cancer, injury, admission to hospital, and mortality: a prospective cohort study The Lancet. ,vol. 386, pp. 1945- 1954 ,(2015) , 10.1016/S0140-6736(15)00235-4
Esther Roura, Xavier Castellsagué, Michael Pawlita, Noémie Travier, Tim Waterboer, Núria Margall, F. Xavier Bosch, Silvia de Sanjosé, Joakim Dillner, Inger T. Gram, Anne Tjønneland, Christian Munk, Valeria Pala, Domenico Palli, Kay-Tee Khaw, Ruanne V. Barnabas, Kim Overvad, Françoise Clavel-Chapelon, Marie-Christine Boutron-Ruault, Guy Fagherazzi, Rudolf Kaaks, Annekatrin Lukanova, Annika Steffen, Antonia Trichopoulou, Dimitrios Trichopoulos, Eleni Klinaki, Rosario Tumino, Carlotta Sacerdote, Salvatore Panico, H. Bas Bueno-de-Mesquita, Petra H. Peeters, Eiliv Lund, Elisabete Weiderpass, M. Luisa Redondo, María-José Sánchez, Maria-José Tormo, Aurelio Barricarte, Nerea Larrañaga, Johanna Ekström, Maria Hortlund, David Lindquist, Nick Wareham, Ruth C. Travis, Sabina Rinaldi, Massimo Tommasino, Silvia Franceschi, Elio Riboli, Smoking as a major risk factor for cervical cancer and pre‐cancer: Results from the EPIC cohort International Journal of Cancer. ,vol. 135, pp. 453- 466 ,(2014) , 10.1002/IJC.28666
Fiona McKenzie, Pietro Ferrari, Heinz Freisling, Veronique Chajès, Sabina Rinaldi, Jordi de Batlle, Christina C Dahm, Kim Overvad, Laura Baglietto, Laureen Dartois, Laure Dossus, Pagona Lagiou, Dimitrios Trichopoulos, Antonia Trichopoulou, Vittorio Krogh, Salvatore Panico, Rosario Tumino, Stefano Rosso, H. Bas Bueno-de-Mesquita, Anne May, Petra H Peeters, Elisabete Weiderpass, Genevieve Buckland, Maria-Jose Sanchez, Carmen Navarro, Eva Ardanaz, Anne Andersson, Malin Sund, Ulrika Ericson, Elisabet Wirfält, Tim J Key, Ruth C Travis, Marc Gunter, Elio Riboli, Anne-Claire Vergnaud, Isabelle Romieu, Healthy lifestyle and risk of breast cancer among postmenopausal women in the European Prospective Investigation into Cancer and Nutrition cohort study International Journal of Cancer. ,vol. 136, pp. 2640- 2648 ,(2015) , 10.1002/IJC.29315
Qing Pang, Kai Qu, Jingyao Zhang, Xinsen Xu, Sushun Liu, Sidong Song, Ruitao Wang, Lingqiang Zhang, Zhixin Wang, Chang Liu, Cigarette smoking increases the risk of mortality from liver cancer: A clinical-based cohort and meta-analysis. Journal of Gastroenterology and Hepatology. ,vol. 30, pp. 1450- 1460 ,(2015) , 10.1111/JGH.12990
Alina Macacu, Philippe Autier, Mathieu Boniol, Peter Boyle, Active and passive smoking and risk of breast cancer: a meta-analysis Breast Cancer Research and Treatment. ,vol. 154, pp. 213- 224 ,(2015) , 10.1007/S10549-015-3628-4
Chelsea Catsburg, Anthony B. Miller, Thomas E. Rohan, Active cigarette smoking and risk of breast cancer. International Journal of Cancer. ,vol. 136, pp. 2204- 2209 ,(2015) , 10.1002/IJC.29266
V Bagnardi, M Rota, E Botteri, I Tramacere, F Islami, V Fedirko, L Scotti, M Jenab, F Turati, E Pasquali, C Pelucchi, C Galeone, R Bellocco, E Negri, G Corrao, P Boffetta, C La Vecchia, Alcohol consumption and site-specific cancer risk: a comprehensive dose-response meta-analysis British Journal of Cancer. ,vol. 112, pp. 580- 593 ,(2015) , 10.1038/BJC.2014.579
Jiemin Cheng, Yi Chen, Xiaolin Wang, Jianhua Wang, Zhiping Yan, Gaoquan Gong, Guoping Li, Changyu Li, Meta-analysis of prospective cohort studies of cigarette smoking and the incidence of colon and rectal cancers. European Journal of Cancer Prevention. ,vol. 24, pp. 6- 15 ,(2015) , 10.1097/CEJ.0000000000000011
R. Talamini, J. Polesel, S. Gallus, L. Dal Maso, A. Zucchetto, E. Negri, C. Bosetti, E. Lucenteforte, G. Boz, S. Franceschi, D. Serraino, C. La Vecchia, Tobacco smoking, alcohol consumption and pancreatic cancer risk: a case-control study in Italy. European Journal of Cancer. ,vol. 46, pp. 370- 376 ,(2010) , 10.1016/J.EJCA.2009.09.002