Novel and potent biological antioxidants on membrane phospholipid peroxidation: 2-hydroxy estrone and 2-hydroxy estradiol.
作者： Minoru Nakano , Katsuaki Sugioka , Isao Naito , Susumu Takekoshi , Etsuo Niki
DOI: 10.1016/0006-291X(87)91501-4
关键词:
摘要: Abstract Catechol estrogens, 2-hydroxy estrone, estradiol and estriol, were tested as possible antioxidants of phospholipid peroxidation induced by Fe 3+ -ADP-adriamycin, using liposomes lipid source α-tocopherol or other steroids reference compounds. The parameters antioxidant activities were: elongation induction period, inhibition O 2 consumption required for peroxidative cleavage unsaturated phospholipid. Of the compounds, estrone had more potent activity than that tocopherol.
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