A Novel Poly(ionic liquid) Interface-Free Two-Dimensional Monolithic Material for the Separation of Multiple Types of Glycoproteins
作者： Cuicui Liu , Qiliang Deng , Guozhen Fang , Xuan Huang , Shuo Wang
关键词:
摘要: Currently, many types of affinity materials have been developed for the enrichment glycoproteins potentially considered to be clinical biomarkers; however, they can not effectively distinguish between different and thus lack functionality that may key diagnosis specific diseases. In present work, a novel interface-free 2D monolithic material has separation multiple glycoproteins, in which boronate-functionalized graphene acts as preconcentration segment poly(guanidinium ionic liquid) segment. The resultant was characterized by X-ray photoelectron spectroscopy, elemental analysis, electroosmotic flow analysis demonstrate successful modification at each step. performance this evaluated capillary electrochromatography allowed online concentration five standard glycoproteins. high efficiency largely attribute...
acs.org
sci-hub.se 参考文章(45)
Felix J. Kohl, Laura Sánchez-Hernández, Christian Neusüß, Capillary electrophoresis in two-dimensional separation systems: Techniques and applications ELECTROPHORESIS. ,vol. 36, pp. 144- 158 ,(2015) , 10.1002/ELPS.201400368
Rajendar Bandari, Jürgen Kuballa, Michael R. Buchmeiser, Ring‐opening metathesis polymerization‐derived, lectin‐functionalized monolithic supports for affinity separation of glycoproteins Journal of Separation Science. ,vol. 36, pp. 1169- 1175 ,(2013) , 10.1002/JSSC.201201042
Robin D Rogers, Kenneth R Seddon, Ionic Liquids--Solvents of the Future? Science. ,vol. 302, pp. 792- 793 ,(2003) , 10.1126/SCIENCE.1090313
Yuanqi Lu, Dunqing Wang, Chunyan Kong, Hao Zhong, Michael C. Breadmore, Analysis of aromatic acids by nonaqueous capillary electrophoresis with ionic‐liquid electrolytes Electrophoresis. ,vol. 35, pp. 3310- 3316 ,(2014) , 10.1002/ELPS.201400242
Cinzia Chiappe, Christian Silvio Pomelli, Point‐Functionalization of Ionic Liquids: An Overview of Synthesis and Applications European Journal of Organic Chemistry. ,vol. 2014, pp. 6120- 6139 ,(2014) , 10.1002/EJOC.201402093
Yanhong Liu, Rui Ma, Qiliang Deng, Lingling Zhang, Cuicui Liu, Shuo Wang, Preparation of ionic liquid polymer materials and their recognition properties for proteins RSC Advances. ,vol. 4, pp. 52147- 52154 ,(2014) , 10.1039/C4RA05713A
Haihong Bai, Yiting Pan, Wei Tong, Wanjun Zhang, Xiaojun Ren, Fang Tian, Bo Peng, Xin Wang, Yangjun Zhang, Yulin Deng, Weijie Qin, Xiaohong Qian, Graphene based soft nanoreactors for facile "one-step" glycan enrichment and derivatization for MALDI-TOF-MS analysis. Talanta. ,vol. 117, pp. 1- 7 ,(2013) , 10.1016/J.TALANTA.2013.08.031
Ilja Tabujew, Christoph Freidel, Bettina Krieg, Mark Helm, Kaloian Koynov, Klaus Müllen, Kalina Peneva, The Guanidinium Group as a Key Part of Water-Soluble Polymer Carriers for siRNA Complexation and Protection against Degradation Macromolecular Rapid Communications. ,vol. 35, pp. 1191- 1197 ,(2014) , 10.1002/MARC.201400120
Shifang Yuan, Qiliang Deng, Guozhen Fang, Mingfei Pan, Xiaorui Zhai, Shuo Wang, A novel ionic liquid polymer material with high binding capacity for proteins Journal of Materials Chemistry. ,vol. 22, pp. 3965- 3972 ,(2012) , 10.1039/C2JM14577D
Verónica Pino, Ana M. Afonso, Surface-bonded ionic liquid stationary phases in high-performance liquid chromatography—A review Analytica Chimica Acta. ,vol. 714, pp. 20- 37 ,(2012) , 10.1016/J.ACA.2011.11.045