Omega-3 fatty acids improve behavioral coping to stress in multiparous rats.

摘要: Behavioral coping refers to the ability modify behavior escape from stress, and is protective against development of depressive disorders. Omega-3 fatty acid (n-3 FA) intake inversely correlated with anxiety depression in humans. The objective this study was determine if consumption n-3 FAs promotes adaptive behaviors a multiparous rat model. Twenty female rats were randomly assigned diets or without FA containing menhaden oil sunflower as fat source, respectively. Rats experienced two cycles gestation lactation. testing began on second day after last parturition. consuming displayed improved learning shuttle box test. Specifically, escaped footshock more quickly had greater number successful escapes than not FAs. Diet did affect general activity open field, but showed less reactivity habituation novelty field Immobility swimming forced swim test, risk-taking assessed by light/dark sucrose drinking, motor coordination significantly affected diet. A diet enriched promoted behavioral changes consistent increased stressful events, suggesting that may help prevent stress-related