Comprehensive profiling of the human circulating endocannabinoid metabolome: clinical sampling and sample storage parameters
作者： JodiAnne T. Wood , John S. Williams , Lakshmipathi Pandarinathan , Amber Courville , Melissa R. Keplinger
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摘要: Background Endogenous cannabinoid-receptor ligands (endocannabinoids) and over a dozen related metabolites now comprise the “endocannabinoid metabolome”. The diverse (patho)physiological roles of endocannabinoids, predictive/diagnostic utility systemic endocannabinoid levels, growing interest in endocannabinoid-related pharmacotherapeutics mandate valid clinical protocol for processing human blood that does not jeopardize profiling circulating metabolome.
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